Understanding Avanair 200 mg: A Comprehensive Guide

Avanair (Avanafil) is the newest available PDE-5 inhibitor and is considered a second-generation PDE5 inhibitor, along with other medications; however, it is the only one that has undergone clinical testing. This article discusses Avanair 200 mg, including its uses, dosing, precautions, and side effects.

Avanair: An Overview

Erectile dysfunction, also called ED, is the persistent inability to get and sustain an erection adequate for satisfactory intercourse. ED management aims to control and reduce associated heart-related problems and to restore the capacity to attain a firm penile erection. ED can be managed with phosphodiesterase (PDE-5) inhibitors, which are considered the first-line therapy. Since oral phosphodiesterase-5 (PDE-5) such as Sildenafil, Tadalafil, and Vardenafil have demonstrated effectiveness in the number and duration of erections in men with ED, PDE-5 have been considered the first-line treatment for erection problems.

Avanair 200 mg uses: Avanair 200 mg is an ED drug that recently received FDA approval for ED management. It is a new PDE5 inhibitor similar to tadalafil, vardenafil, and sildenafil.    

Dosing and administration 

The usual prescribed dosage is 100 mg, to be taken as required around 15 to 30 minutes before indulging in sexual intercourse, but keep in mind that sexual stimulation is required for a response to this ED therapy. Based on individual effectiveness and tolerability, the daily dose of Avanair may be increased to 200 mg or decreased to 50 mg. According to most doctors, the maximum dosing frequency is once daily.   

No need for dose adjustments in patients aged 65 years or older. However, the available data on individuals aged 70 or older is limited. Dose adjustments are not required in patients with diabetes mellitus or mild to moderate kidney impairment. For those who are suffering from mild to moderate hepatic insufficiency, treatment should be started with a minimum effective dose and should be adjusted based on tolerance. Avanair is contraindicated in patients with severe renal and hepatic impairment. Doctor consultation and a prescription are important for men of all ages who consider any ED drug.

Effectiveness of Avanafil

Avanair 200 mg contains the active ingredient Avanafil, another PDE-5 inhibitor, which competes with sildenafil, vardenafil, and tadalafil as a treatment for ED. By inhibiting phosphodiesterase-5, these drugs cause smooth muscle relaxation, allowing blood to flow in and resulting in an erection. The tablets are rapidly absorbed. Maximum effects are reached within 30 to 45 minutes, and in some men, erection occurs within 20 minutes of taking a 200 mg dose of Avanair. The absorption of medicine is delayed by food; therefore, the medicine may take longer to work after eating. 

Contraindications

The coadministration of organic nitrates is contraindicated. If nitrate is required and considered necessary in a life-threatening situation, there should be a gap of at least 12 hours since a dose of Avanair was taken. 

Warnings and precautions 

• There is cardiovascular risk associated with Avanair during sexual activity in patients with preexisting cardiovascular disorders. Avanafil should not be taken by men whose healthcare professional has instructed them to abstain from sexual activity because of a history of heart disease. 

Avanair should not be used in the following populations:

• People who have had a stroke, myocardial infarction, or coronary revascularization within the last six months.
• Men with resting hypertension and hypotension.
• Patients with congestive heart failure
• Men with unstable angina or angina that occurs during sexual intercourse.

• The ED medication is believed to have vasodilatory properties that can have an effect on antihypertensive medications and increase the blood pressure-lowering effects. 
• Erections that last for more than four hours and priapism have been reported with the use of PDE5 inhibitors; therefore, besides Avanair 200 mg benefits, patients trying their hands on Avanair need to be educated about its unwanted effects, too. Exercise caution if Avanafil is prescribed in patients who have a deformity of the penis or in patients who have other health issues that may predispose them to priapism. 
• Treatment discontinuation should be considered if the user develops loss of eyesight in one or both eyes. This could be an indication of permanent vision loss.
• Other PDE5 inhibitors have been observed to cause a sudden reduction or complete loss of hearing, which can be accompanied by tinnitus or dizziness. Those who experience any of these symptoms should discontinue the treatment immediately.
• Avanair should be cautiously used in patients taking alpha-blocker medications because of the vasodilating effects of the PDE5 inhibitors. If an alpha-blocker medication is introduced, the treatment must be started on men who are concomitantly taking Avanair tablets; the alpha-blocker medication should be started at the lowest dose, and treatment should be continued with slow changes.

Adverse reactions or Side effects of Avanafil

The most commonly reported side effects of this ED medication are congestion, flushing, acne, nasopharyngitis, and back pain. Other rare but serious side effects associated with the drug are bronchitis, constipation, dyspepsia, hypertension, influenza, upper respiratory tract infection, sinus congestion, nausea, and rash. Dizziness, arthralgia, back pain, and diarrhea were also reported in the clinical trials. 

Conclusion

Avanafil Avanair 200mg offers an effective and fast-acting solution for men dealing with erection issues. With its potent active ingredient, Avanafil, it provides rapid relief, allowing a man to attain and sustain a satisfactory erection. One can achieve an erection within just 15 to 30 minutes of taking the tablet. For optimal results and to minimize side effects, take the tablet under the guidance of a healthcare professional.