How Does Triluma Cream Work?

Triluma cream is a powerful prescription for people with moderate to severe melasma. If you are looking for a more even skin tone and are wondering if you can use Triluma cream and how it works, then you have turned to the right page. 

About Triluma cream

Triluma cream is the only FDA-approved topical treatment available to help reduce the appearance of dark spots associated with moderate to severe melasma. The fixed-dose combination containing hydroquinone, tretinoin, and fluocinolone acetonide for facial melasma, a common skin problem that causes dark patches on the face. It sometimes develops due to hormone changes. Hyperpigmentation is especially common in darker patients and is often tough to treat. Hydroquinone, tretinoin, and topical corticosteroids are the most effective therapeutic agents for treating hyperpigmentation and melasma. Once daily formulation triple combination cream containing 0.05% tretinoin, 4% hydroquinone, and 0.01 %fluocinolone acetonide represents the only commercially available combo of all three pharmaceutical agents. 

How it works?

Triluma is the only approved topical prescription, fixed-dose combination containing hydroquinone for facial melasma. The three ingredients work in the following ways:

1. Fluocinolone acetonide: It is a mild topical corticosteroid with anti-inflammatory effects. It helps to minimize the irritative effects of the two other agents and inhibits melanin by lowering cellular metabolism. 

1. Hydroquinone – A well-known depigmenting agent that interferes with the formation and synthesis of melanin to help even and lighten the skin tone.

1. Tretinoin: It is a retinoid formulation that may prevent oxidation of hydroquinone and improve skin penetration and skin cell turnover, allowing pigment elimination and reducing the risk of skin atrophy.

You are not alone if you think you may be struggling with melasma. It has been estimated that over 5 million people are affected by melasma. The exact cause of the skin condition is not known, but it is believed to be triggered by excessive sun exposure, pregnancy, use of contraceptive pills, and hormone therapy treatments. While melasma can affect anyone, people with darker skin tones are more likely to get melasma. 

Triluma improves melasma

No doubt, triluma cream may improve the skin tone by improving the appearance of facial melasma. But it is not a cure and should always be combined with sun avoidance measures. Even a small amount of sun exposure can trigger or worsen melasma. 

Possible side effects 

Some patients may develop severe allergic reactions to Tri-luma cream. It contains a corticosteroid as one of its active components. The side effects reported with corticosteroid medicine to the skin are irritation, itching, skin dryness, changes in skin color, acne, hair follicle infection, allergic skin reaction, skin thinning, sweat problems, and stretch marks. 

Some patients using this fixed dose combination drug develop dark spots on their skin, increased skin sensitivity, tingling, and skin redness caused by a skin issue, rosacea. The triple combination product may also give rise to a gradual blue-black darkening of your skin; if this happens, discontinue treatment and immediately seek medical advice.  

Expert’s tips for melasma

• Rinse your hands well after using Tri-luma cream to avoid getting into your eyes. If the formulation gets into your eyes, rinse thoroughly with water. 

• Wash your skin, make sure there is no makeup, and dry the affected areas of your skin well before applying the triple combination cream. Burning sensation or itching after applying the cream are common side effects, but seek immediate medical advice if you develop a rash. 

• Triluma cream might improve the appearance of dark spots and patches on the skin, but it is not a cure for melasma. Once you discontinue treatment, the discolored skin usually returns after several weeks. Speak to your healthcare professional about long-term options you can use after completing your triluma cream course.

• Avoid applying Triluma cream more than once daily. Excessive usage can cause skin irritation and will not yield faster or better results.  

• Hyperpigmentation gets worse when you are exposed to the ultraviolet rays of the sun. This even happens during the winter and on hazy days. 

• To help prevent this, avoid sun exposure and tanning bed, wear protective clothing (full sleeves, hat, and gloves), and use sunscreen with a SPF of at least 30 while using Triluma cream.  

• Hormonal contraceptive methods can also contribute to melasma to become worse. 

• If you are allergic to sulfites, you should not use Triluma cream. The fixed-dose triple combination topical cream contains sulfites. Sulfites are quite different from sulfa medicines, so you can use this medicine if you have a sulfa allergy. 

The more you know about melasma, the better you can control its impact on your skin. Seek medical help for more details and You can buy triluma cream is appropriate for melasma treatment.