Glycomet GP (500+1) mg

Glycomet GP (500+1)mg is an oral antidiabetic medicine that is used to treat type-2 diabetes and limited cases of type-1 diabetes. This medicine contains two main active ingredients: Glimepiride 1 mg and Metformin 500mg. The combination medicine increases and promotes insulin using pancreatic beta cells in your body. This ingredient can also improve body cells' sensitivity to insulin.

In other words, Metformin can suppress glucose production by the liver, and Glimepiride is an oral hypoglycemic medicine that promotes insulin production from pancreatic beta cells. 

Glycomet GP (500+1)mg uses

When taken per regimen, Glycomet-GP 1 tablet, the antidiabetic medication, can considerably lower blood sugar levels over time. This drug is combined with other medicines to treat diabetes, but your doctor can determine the appropriate dosage. This drug must be supported with a well-balanced, calorie-controlled diet comprising healthy fruits and vegetables. Remember that this medicine can only control diabetes, not cure it.

How does Glycomet GP (500+1)mg tablet work?

Metformin hydrochloride, the active ingredient of Glycomet GP, can decrease high blood glucose/hyperglycemia and help your body efficiently utilize insulin released by the pancreas. Moreover, Metformin decreases hepatic gluconeogenesis and, at the same time, decreases intestinal absorption of glucose.

Another active ingredient, Glimepiride, ties along with the potassium channel and depolarizes the membrane. Thereafter, it activates calcium-iron inflow and induces insulin secretion. It can also stimulate the insulin release from functioning pancreatic β-cells and inhibit gluconeogenesis in hepatic cells. Both the ingredients can increase insulin sensitivity to cure type-2 and type-1 (insulin-dependent) diabetes. Metformin is also known to treat the complications of cardiovascular diabetes.

Where to buy Glycomet GP1 online?

You can buy Glycomet GP1 medicine from any renowned online pharmacy. Compare Glycomet GP (500+1)mg price and get the best offers at PRx for doorstep delivery in the promised timeframe. At premiumrxdrugs, you can also check the Glycomet GP (500+1)mg review and product details about the workings, usage, side effects, and precautions of this medicine.

Safety precautions with Glimepiride 1mg and Metformin 500mg tablet

Glycomet GP may interact with some drugs, such as cimetidine, glucocorticosteroids, corticosteroids, tetracosactrin, warfarin, danazol, diuretics, and sulphonylurea.

Apart from these, this medicine's administration with propranolol may increase Cmax, AUC, and T1/2 of Glimepiride. Moreover, coumarins, probenecid, MAOs, salicylates, sulfonamides, chloramphenicol, and beta blockers can change the hypoglycemic action of Glimepiride. Furosemide also increases the Cmax of Metformin.

Glycomet GP 1mg should not be used in patients with known hypersensitivity to Glimepiride, Metformin, or any of the formulation's ingredients. Also, inform your doctor about your existing ailments and the medicine/supplements you may be taking. Pregnant and breastfeeding women should inform their doctor about their physical state for the safe usage of this medicine.

Store Glycomet GP in a cool and dry place, and keep it away from pets and children as it can harm them.

Side effects of Glimepiride 1mg and Metformin 500mg tablet

Some common side effects of this medicine include:

• Vomiting
• Diarrhea
• Metallic taste
• Rash
• Allergic skin reactions
• Leukopenia
• Hemolytic anemia
• Photosensitivity reactions
• Isolated transaminase elevations
• Aplastic anemia
• Cholestatic jaundice
• Agranulocytosis
• Thrombocytopaenia
• Pancytopenia
• Blurred vision

Another side effect is the buildup of lactic acidosis in the body, which could be potentially fatal if you leave it unattended. You have to discuss with your doctor if any side effects of the medicine are affecting your health or bothering you.

How to take?

Usage instructions of Glimepiride 1mg and Metformin 500mg tablet

Glycomet GP (500+1)mg dosage for adults varies from patient to patient, depending on their health condition. The tablet is given once or twice daily. Its dosage should not be more than 1000 mg. The medication course should be continued as recommended by your doctor. Take the tablet with a glass of water after having food. If you have missed a dose, you can consume it the next day in less than an hour of your routine meal. Never double up the dose to compensate for missed doses' damage.