Istavel 100mg Tablet 

Istavel 100mg tablet is an oral diabetes medicine that helps you control blood sugar levels. This medicine can regulate the levels of insulin that your body generates after a meal. Istavel is prescribed only to the people with type-2 diabetes. This medicine can be used alone or in combination with certain other medicines like insulin, metformin, sulphonylureas, and glitazones. Sitagliptin is an active ingredient of of the medicine that can increase the levels of insulin in the body.

 What is Istavel 100mg used for?

Istavel 100mg is a dipeptidyl peptidase-4 inhibitor, which is used as an adjunct to diet and exercise to improve glycemic control in adults with type-2 diabetes mellitus. This medicine can be used alone as well as in combination with certain other medicines as prescribed by your doctor.

How does Istavel 100mg work?

Sitagliptin, an active ingredient of Istavel 100mg, is an anti-diabetic drug that works by increasing levels of natural substances called incretins. These substances help to control blood sugar by increasing insulin release. Insulin is a very crucial hormone that helps to control the levels of sugar in your blood. In this way, Sitagliptin can decrease the amount of sugar that your liver makes. It also reduces the amount of a substance called glucagon that pancreas produces.

What does Istavel 100mg contain?

Istavel 100 mg contains the active substance Sitagliptin, which is a member of a class of medicines called DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors). This ingredient can lower blood sugar levels in adult patients with type 2 diabetes mellitus.

What are the side effects of Istavel 100mg?

The consumers of Istavel drug may experience its side effects such as:

• Hives
• Fast heart rate
• Vomiting
• Difficulty breathing
• Loss of appetite
• Swelling of face, lips, tongue, or throat
• Weight gain
• Less urine release
• Nausea

Some other side effects may include pancreatitis (a severe pain in upper stomach spreading to your back), skin pain, rash, burn feeling in the eyes, headache, muscle pain, etc. You have to stop taking Istavel and tell your doctor right away if you are experiencing allergic reactions to Sitagliptin.

What are the medications interact with Istavel?

Istavel may interact with digoxin, probenecid, non-steroidal anti-inflammatory drugs (NSAIDs), aspirin or other salicylates, sulfa drugs, monoamine oxidase inhibitors (MAOIs), or beta-blockers. There was a slight increase in the area under the curve and mean peak drug concentration of digoxin when it’s administered along with Istavel.

The clinical studies find that Sitagliptin does not meaningfully alter the pharmacokinetics of metformin, glyburide, simvastatin, rosiglitazone, warfarin, sulfonylureas, thiazolidinediones or oral contraceptives. Patients receiving digoxin should be monitored appropriately. No dosage adjustment of digoxin or ISTAVEL is recommended. Clinical data also suggest that Sitagliptin is not susceptible to clinically meaningful interactions with coadministered medications.

 When should Istavel not be used?

There are some cases of inflammation of the pancreas (pancreatitis) in patients taking Istavel. To achieve a better result from Istavel medicine, you have to follow some precautions as:

• Leave alcohol as it can increase the levels of triglycerides in the blood
• Be careful if you have any past or present kidney problems
• Tell your doctor about any allergic reactions to Sitagliptin
• Low blood sugar may occur when taking this medicine in combination with a sulphonylurea medicine
• Severe and disabling arthralgia has been reported in patients taking DPP-4 inhibitors, so discontinue medication if appropriate
• Assessment of renal function is recommended prior to taking this medicine and periodically thereafter.

 How should Istavel be taken?

The recommended dose of Istavel 100mg is once daily. You can take it with or without food. For patients with moderate renal insufficiency, the dose of Istavel is 50 mg once a day is sufficient.

 How long should you take Istavel?

Continue using Istavel 100mg tablet  for as long as your physician recommends you to.

 Missed dose of Istavel?

If you have missed a dose of Istavel 100mg then take it as soon as possible, but, don’t make it double to make up the damage due to the skipped dose.

 How should Istavel be stored?

Store this medicine at room temperature. Keep it away from heat and moisture, and don’t take it if its date has been expired.